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Prof. Dr. med. Jürgen Brockmöller
Prof. Dr. med. Jürgen Brockmöller
Abteilung Klinische Pharmakologie
Georg-August-Universität Göttingen
Robert-Koch-Str. 40
37075 Göttingen
Tel 0551 39 5770
Fax 0551 39 12767
jbrockmoller@gcpg.de
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Jürgen Brockmöller was born in 1958 in Bonn,
Germany. After his medical studies in Berlin, Germany he joint in 1983
the Max-Planck-Institute of Molecular Genetics in Berlin as a PhD-student
in the research group of B.
Wittmann-Liebold, where he worked on the primary structure of ribosomal
proteins and their structural arrangement in the bacterial ribosome. From
1987 to 1993, Jürgen Brockmöller worked as a postdoctoral fellow
at the Institute of Clinical Pharmacology at the University Medical Center
Benjamin Franklin in Berlin under the directorship of H. Kewitz and I. Roots.
In this time, Jürgen Brockmöller specialized in Clinical Pharmacology
and worked on harmacogenetics, pharmacokinetics, drug metabolism and therapeutic
drug monitoring. At this time, he studied genetic polymorphisms in cytochrome
P450 enzymes CYP2C9, CYP2C19 and CYP2D6 and in glutathione S-transferases
M1 and T1 and in arylamine N-acetyltransferases 1 and 2. From 1993 to 2000,
he was senior lecturer at the University Medical Center Charité in
Berlin where his scientific work concentrated on pharmacogenetics. In 2000,
Jürgen Brockmöller became director of the Department of Clinical
Pharmacology of the Medical Faculty of the University Göttingen, Germany.
The department of clinical pharmacology under the directorship of Prof. Brockmöller
has the approval for postgraduate training in clinical pharmacology (Facharzt-Weiterbildungsberechtigung).
Since 1987, Dr. Brockmöller significantly contributed to numerous clinical
trials including phase-I to phase-IV studies of drug development and he conducted
a number of multicentric observational studies including molecular epidemiological
case control studies on [lung cancer] and on [urinary bladder cancer]. More
research included a number of multicentric prospective cohort studies and
meta-analyses on [pharmacogenomic predictors of drug treatment in schizophrenia],
in [depression] and in [cancer drug therapy]. His current research interests
are concentrating on functional Pharmacogenetics and Pharmacogenomics and
clinical application of Pharmacogenetics in medical practice.
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